3. J Allergy Clin Immunol Volume 127, Number 3
a Sudden onset of symptoms and signs is characteristic of anaphylaxis. Symptom patterns vary from one patient to another, and even in the same patient, from one anaphylactic episode to another. Only a few symptoms might be present.
b The purpose of listing signs and symptoms in this Table is to aid in prompt recognition of the onset of anaphylaxis and to indicate the possibility of rapid progression to multiorgan system involvement, not to grade severity.
c Skin and mucosal symptoms are reported to occur in 80-90% of patients with anaphylaxis, respiratory tract involvement in up to 70%, gastrointestinal tract involvement in up to 45%, cardiovascular system involvement in up to 45%, and central nervous system involvement in up to 15%.