Advice for
healthcare
professionals1,2

  • It is recommended that patients are prescribed two EpiPen Auto-Injectors which they should carry at all times.
  • The physician prescribing an EpiPen Auto-Injector must ensure that the patient understands the indications for use and the correct method of application. Therefore, the physician should discuss the patient information leaflet, the correct handling of the Auto-Injector and the possible symptoms of an anaphylactic shock in detail with the patient.
  • An initial dose should be administered as soon as symptoms of anaphylaxis are recognized.In the absence of clinical improvement or if deterioration occurs, a second injection with an additional EpiPen
    Auto-Injector may be administered 5 - 15 minutes after the first injection.
  • It is strongly advised also to educate the patient’s immediate associates (e.g. parents, caregivers, teachers) for the correct usage of the EpiPen in case support is needed in the emergency situation.

References

  • EpiPen (adrenaline) 300 micrograms solution for injection in pre-filled pen, Summary of Product Characteristics. Available at: www.medicines.ie. Last accessed: 24th October 2025.
  • EpiPen Junior (adrenaline) 150 micrograms solution for injection in pre-filled pen, Summary of Product Characteristics. Available at: www.medicines.ie. Last accessed: 24th October 2025.

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